Cáncer pulmonar el peor efecto del tabaquismo / Lung cancer the worst effect of smoking

Lung cancer is the first cause of death in Chilean cancer patients. Globally it accounts for more than 8 million annual deaths. Of the new cases of cancer, more than 6 million are smoking related, making smoking the most important cancer risk factor and the cause of about 20 % of the global cancer-related mortality. The incidence of lung cancer is directly associated with smoking exposure levels during life, exposure that increases the risk of this disease up to 30 times. This risk decreases exponentially with smoking cessation, especially if it occurs in early life stages. In Chile, 85 % of lung cancers in men and 40 % in women may be explained by smoking, equivalent to 1926 per year. Brief counseling is recommended according to the Clinical Guidelines for the Treatment of Smoking in Chile 2017, and if that is not possible, all smokers with cancer should be referred to smoking cessation therapy, which may be done by telephone (6003607777, Salud Responde Program, MINSAL; the number is on cigarette packets).

El cáncer de pulmón constituye la primera causa de muerte por cáncer en Chile. A nivel mundial da cuenta de más de 8 millones de fallecimientos anuales, de los nuevos casos de cáncer, más de 6 millones están relacionados con tabaco, constituyendo el tabaquismo un importante factor de riesgo y causa directa de cerca del 20% de la mortalidad global asociada a cáncer. La incidencia de cáncer de pulmón está directamente relacionada el nivel de exposición a tabaquismo durante la vida, la exposición puede aumentar el riesgo de esta enfermedad hasta 30 veces. El riesgo disminuye exponencialmente con la cesación de esta adicción, especialmente si ocurre en etapas tempranas de la vida. En Chile el 85% de los cánceres de pulmón en hombres y el 40% en mujeres estarían explicados por tabaquismo, equivalentes a 1926 anuales, siendo la recomendación realizar consejería breve según las Guías Clínicas de Tratamiento del Tabaquismo Chile 2017 y si no es posible derivar a todos los fumadores con cáncer a terapia de cesación del tabaquismo que puede ser telefónica Salud Responde MINSAL 6003607777, el numero está en las cajetillas de cigarrillos.

Cáncer pulmonar el peor efecto del tabaquismo / Lung cancer the worst effect of smoking

Resumen El cáncer de pulmón constituye la primera causa de muerte por cáncer en Chile. A nivel mundial da cuenta de más de 8 millones de fallecimientos anuales, de los nuevos casos de cáncer, más de 6 millones están relacionados con tabaco, constituyendo a el tabaquismo un importante factor de riesgo y causa directa de cerca del 20% de la mortalidad global asociada a cáncer. La incidencia de cáncer de pulmón está directamente relacionada el nivel de exposición a tabaquismo durante la vida, la exposición puede aumentar el riesgo de esta enfermedad hasta 30 veces. El riesgo disminuye exponen-cialmente con la cesación de esta adicción, especialmente si ocurre en etapas tempranas de la vida. En Chile el 85% de los cánceres de pulmón en hombres y el 40% en mujeres estarían explicados por tabaquismo, equivalentes a 1926 anuales, siendo la recomendación realizar consejería breve según las Guías Clínicas de Tratamiento del Tabaquismo Chile 2017 y si no es posible derivar a todos los fumadores con cáncer a terapia de cesación del tabaquismo que puede ser telefónica Salud Responde MINSAL 6003607777, el número está en los envases de cigarrillos.

Lung cancer is the first cancer death in Chile. Globally accounts for more than 8 million annual deaths, of the new cases of cancer, more than 6 million are smoking related, making smoking the most important cancer risk factor and cause of about 20% of the global cancer-related mortality. The incidence of lung cancer is directly related to smoking exposure level during life, exposure that increases the risk of this disease up to 30 times. This risk decreases exponentially with smoking cessation, especially if it occurs in early life stages. In Chile, 85% of lung cancers in men and 40% in women would be explained by smoking, equivalent to 1926 per year, being recommended to conduct brief counseling according to the Clinical Guidelines for the Treatment of Smoking in Chile 2017, and if it is not possible to refer all smokers with cancer to smoking cessation therapy that may be by telephone Salud Responde, MINSAL 6003607777, the number is in the cigarette packets.

[Umbilical cord hematopoietic precursors transplantation. Report of five patients]. / Trasplante con precursores hematopoyéticos de cordón umbilical en adultos con neoplasias hematológicas en Chile: serie clínica.

Hematopoietic precursors transplantation is a therapeutic alternative for leukemia, some metabolic diseases and some immune deficiency syndromes. In its allogeneic variety leukemia eradication is based in the conditioning prior to transplantation and the allograñ effect against leukemia. Umbilical cord blood is an alternative source of hematopoietic precursors when there are no HLA compatible relatives available. Between 2003 and 2007 we have performed five umbilical cord blood transplant in adult patients in a University hospital. All patients had malignant diseases. Conditioning protocols were ablative in all except in one patient and in all, more than one unit of umbilical cord blood was used. Hematopoietic engraftment was confirmed in all patients and the main complications registered were infectious and associated to immunosuppression.

Trasplante con precursores hematopoyéticos de cordón umbilical en adultos con neoplasias hematológicas en Chile: Serie clínica / Umbilical cord hematopoietic precursors transplantation: Report of five patients

Hematopoietic precursors transplantation is a therapeutic alternative for leukemia, some metabolic diseases and some immune deficiency syndromes. In its allogeneic variety leukemia eradication is based in the conditioning prior to transplantation and the allograñ effect against leukemia. Umbilical cord blood is an alternative source of hematopoietic precursors when there are no HLA compatible relatives available. Between 2003 and 2007 we have performed five umbilical cord blood transplant in adult patients in a University hospital. All patients had malignant diseases. Conditioning protocols were ablative in all except in one patient and in all, more than one unit of umbilical cord blood was used. Hematopoietic engraftment was confirmed in all patients and the main complications registered were infectious and associated to immunosuppression.